Can We Skip Surgery in Bladder Cancer?

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Published Jun 28, 2025

In this segment, Dr. Karine Tawagi explores a key question in modern urinary bladder cancer treatment: Can we skip surgery for certain patients? From new trials to the role of ctDNA in guiding decisions, she walks us through how personalized bladder cancer treatment is reshaping what’s possible—especially for those aiming for bladder preservation.

What you'll learn in this conversation:
▶ The potential of non-surgical bladder cancer treatment and how ctDNA bladder cancer monitoring can guide who’s eligible
▶ How the surgical treatment of bladder cancer affects quality of life—and when it may be avoidable
▶ Where enfortumab vedotin fits into frontline urothelial carcinoma care and how side effects can be managed
▶ Real-world implications of cancer treatment equity and access to novel therapies like immunotherapy
▶ The current landscape for treatment of bladder cancer by stage, including metastatic disease and promising survival strategies
▶ Why combining biomarkers, chemo-immunotherapy, and ctDNA is driving a shift in bladder cancer treatment options

This episode looks at how smarter tools and a patient-centered approach may finally help reduce the need for invasive surgery without compromising outcomes.

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