Capivasertib Plus Abiraterone in Metastatic Prostate Cancer

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Published
Join Dr. Karan Jitwani and Dr. Alan Bryce in this insightful podcast episode as they delve into the latest developments in prostate cancer research, focusing on the CAPItello-280 and CAPItello-281 studies. Dr. Bryce, a leading expert in genitourinary cancers, provides a historical context for these important studies and discusses the implications of the recent CAPItello-281 results presented at ASCO 2026.
In this episode, you'll learn about:
• The role of the androgen receptor in prostate cancer and its parallels with breast cancer treatment strategies
• The significance of the new terminology introduced by the Prostate Cancer Working Group 4, shifting from "castration-resistant" to "androgen pathway modulator-resistant"
• The primary and secondary endpoints of the CAPItello studies, including the implications of positive radiographic progression-free survival (rPFS) results versus disappointing overall survival (OS) outcomes
• The challenges and considerations regarding the toxicity of cabozantinib and its impact on patient quality of life

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Tune in for a comprehensive discussion that sheds light on the evolving landscape of prostate cancer treatment and the critical questions that arise from recent clinical trial results.

#ProstateCancer #CAPItello281 #mCRPC #GUOncology #ClinicalTrials #MedEd
Categoria
Oncology
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