How Multi-Organ Imaging is Transforming Cardio-Kidney-Metabolic Practice | Dr Y S Chandrashekhar

"Late Gadolinium Enhancement (LGE) has officially surpassed Ejection Fraction as the gold standard for predicting cardiac risk because it identifies the actual 'dead zones' that volume checks miss," said Professor Y. S. Chandrashekhar in a conversation with Dr. P.C. Manoria at the World Congress Cardio Kidney Metabolic (WC CKM) Medicine 2026.

Here are the top 5 takeaways from the conversation:

1 LGE over EF: Late Gadolinium Enhancement is now superior to Ejection Fraction for distinguishing viable tissue from dead scar.
2 15% Scar Rule: Scars exceeding 15% in non-ischemic patients predict sudden death risk, even if pump function appears normal.
3 Pattern Signatures: Scar location acts as a fingerprint—sub-endocardial indicates coronary disease, while ring-like patterns warn of fatal arrhythmias.
4 Hidden Inflammation: Precision care now targets perivascular fat and microvascular resistance to catch inflammation missed by standard angiograms.
I5 ntegrated Care: The rise of multi-organ disease necessitates a Cardiometabolic Physician for unified, precision prevention.

Dr. Y. S. Chandrashekhar is a globally distinguished cardiologist and the Editor-in-Chief of JACC: Cardiovascular Imaging. He is a Professor of Medicine and a leading authority on advanced cardiac imaging techniques. Dr. Chandrashekhar is renowned for his research into myocardial viability and his leadership in defining how modern imaging like Cardiac MRI and CT can be used to predict and prevent adverse cardiovascular events.

Dr. Professor P.C. Manoria is the Executive President for the World Congress Cardio Kidney Metabolic (WC CKM) Medicine. He is a distinguished cardiologist based in Mumbai and is a prominent figure in the integration of cardio-renal-metabolic care. Dr. Manoria has led numerous international medical congresses aimed at addressing the epidemic proportions of non-communicable diseases in South Asia.

Video Timestamps:
0:00 Introduction to WC CKM 2026 and the Indispensability of Imaging
1:17 The Superiority of LGE over Traditional Wall Thinning Techniques
2:14 Size Matters: The 15% Threshold for Sudden Cardiac Death Risk
3:38 Interpreting Scar Location: Ischemic vs. Non-Ischemic Signatures
5:10 The New "Ring-Like" Enhancement and Arrhythmic Clues\
6:27 Comparing Viability Markers: MRI vs. PET and Dobutamine Echo
8:39 Perivascular Fat: A Non-Invasive Window into Vascular Inflammation
11:29 Assessing Microvascular Dysfunction: IMR and the "Silent" Angina
16:07 Closing Remarks: The Rise of the Cardiometabolic Physician

#WCCKM2026 #DrYSChandrashekhar #DrPCManoria #JACCImaging #CardiacMRI #LGE #Cardiology #CardiometabolicMedicine #HeartHealth #PrecisionImaging #TheRightDoctors #trding

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