Immune Related Adverse Events (irAEs): Endocrinopathies

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Dr. Benjamin Schlechter, an oncologist at Dana Farber Cancer Center, explains how to recognize and treat checkpoint inhibitor induced endocrinopathies.

Key Points:
1. If considering endocrinopathies, make sure to rule out brain metastases!
2. Important labs: ACTH, TSH/T4, AM cortisol, prolactin
3. Always involve an endocrinologist to help:
a) guide hormone supplementation
b) educate patients about stress dose steroids/ adrenal crisis prevention
4. Steroids may prevent optic chiasm injury

Interested in learning more about checkpoint inhibitors and immune related adverse events (irAEs)?:
1. Explore our irAEs YouTube playlist: https://www.youtube.com/playlist?list=PLD6maWB-VZPBUsWcMTBoKQ73qMRcrozdh
2. Check out the full podcast episode at our website: https://www.coreimpodcast.com

#oncology, #immunotherapy, #checkpointinhibitors, #IRAEs, #internalmedicine, #medicaleducation,#residency, #CoreIM, #IMcore

Original interview by Shreya P. Trivedi MD and Anu Gupta MD.
Video content and editing by Chloe Gordon MD and Alice Kennedy MD.
Category
Oncology
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