Optimizing post-CAR T-cell monitoring in lymphoma: evidence with the use of liso-cel

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Manali Kamdar, MD, University of Colorado Cancer Center, Denver, CO, discusses research exploring how to optimize post-CAR T-cell monitoring in patients receiving lisocabtagene maraleucel (liso-cel), commenting on the potential to shorten the mandated four-week requirement for patients to stay within a certain radius of the treating academic center after receiving CAR-T therapy. Dr Kamdar highlights that the majority of adverse events, including cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS), occur within the first 15 days after infusion, suggesting that a shorter monitoring period may be sufficient. This interview took place during the 2025 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL.

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Oncology
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