Radiation Therapy for Invasive Lobular Breast Cancer: Uncovering an Overlooked Opportunity

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Matthew Sikora, PhD, discusses a narrative review examining why invasive lobular carcinoma (ILC)—the second most common type of breast cancer—may be more sensitive to radiation therapy than previously recognized. The discussion covers the unique biology of ILC, potential DNA repair defects driving radiosensitivity, and how these insights could guide more tailored radiation strategies. Dr. Sikora addresses gaps in current guidelines, the lack of prospective data, and opportunities for using molecular and imaging markers to optimize radiation use in both localized and metastatic settings.

#invasivelobularcarcinoma #cancerresearch #breastcancer #oncology #radiationtherapy
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Oncology
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