The Cholesterol Data That Didn’t Fit the Narrative

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Published
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What if a medication can raise LDL cholesterol yet still reduce cardiovascular deaths? In this video, I walk through the science behind SGLT2 inhibitors. We will discuss a landmark trial published in The New England Journal of Medicine, dive deeper into the mechanism using new animal and human data published in Nature Aging. This isn’t a video about a simple drug, but a case study in how cholesterol narratives are built.

Chapters
0:00 – A Paradox: A Drug That Raises LDL but Saves Lives
1:32 – Roadmap: Cholesterol Narratives, Clinical Trials, and Mechanisms
2:12 – Chapter 1: The Pattern. LDL is “Bad” Cholesterol
5:45 – Chapter 2: SGLT2 Inhibitor and a Major Clinical Trial
10:18 – Chapter 3: Mechanisms and Mysteries! How They Work
14:12 – Proof People Want Nuance…

#CardiovascularHealth #LDL #Cholesterol #ApoB #HDL #SGLT2 #Diabetes #HeartDiseaseResearch #Longevity #AMPK #RCT #KetogenicDiet #FastingScience #MetabolicHealth #Atherosclerosis #CardiovascularDisease #InsulinResistance #Obesity #Healthspan #EvidenceBasedMedicine #ClinicalTrials #MedicalEducation #PreventiveCardiology #SystemsBiology #StayCurious #Metabolism
Categoria
Cardiology
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