The Future of Cancer Treatment: Understanding Tumour Resistance with PERSIST-SEQ

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Welcome to episode 1 of the PERSIST-SEQ video series, where we take you behind the scenes of cutting edge-research into treatment-resistant cancers. In this episode, we speak with Ultan McDermott from AstraZeneca, a key partner in this EU-funded consortium.

In this video, you’ll hear about:

????Why focusing on drug-tolerant persister cells is key to understanding tumour persistence

???? How collaborations among industry, academia and service providers are vital for accelerating cancer research

???? The cutting-edge technology PERSIST-SEQ is using, like single cell sequencing, spatial transcriptomics, tumour organoids and patient-derived xenografts.

What is PERSIST-SEQ?

PERSIST-SEQ is an Innovative Medicines Initiative 2 project. This public-private partnership is focused on understanding why and how tumours persist. By using single-cell sequencing, patient-derived organoids and xenografts, researchers across Europe aim to create reproducible workflows for studying tumour persistence. The consortium focuses on understanding tumour plasticity, particularly drug-tolerant persister cells.

To learn more about PERSIST-SEQ:

Head to our website https://persist-seq.org/

Find us on LinkedIn https://www.linkedin.com/shareArticle?url=https://persist-seq.org/contact&source=

If you have any questions about PERSIST-SEQ, please contact the PERSIST-SEQ secretariat: [email protected]

????‍????Who is this video for?

????Cancer researchers and clinicians

???? Policy makers, regulators and healthcare innovators

???? Patients, advocates, and curious members of the public

Keywords:

Cancer research, oncology, therapeutic resistance, drug resistance, single cell sequencing, spatial transcriptomics, open science, patient derived organoids, patient derived xenografts, collaboration, personalised medicine, science communication #cancer #research #oncology

Credits and acknowledgements:

Drone footage courtesy of AstraZeneca PLC, used with permission.
Category
Oncology
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