TIL Therapy Revolution: 96% Survival & 67% Response in Melanoma - Dr. Allison Betof Warner

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ARTICLE: https://oncologytube.com/til-therapy-breakthroughs-oncologists/
Join Dr. Allison Betof Warner, Director of the Melanoma Program at Stanford, as she unveils groundbreaking advances in TIL (Tumor-Infiltrating Lymphocyte) therapy for melanoma. Discover how lifileucel achieves a 96% 10-year survival rate for responders and how engineered OBX-115 delivers a 67% response rate in PD-1 refractory cases. Learn about the TILVANCE-301 trial, safety innovations, and the future of oncology beyond melanoma. Recorded October 2025.

Timestamps

[00:00] - Teaser: 96% Survival & 67% Response in Melanoma
[00:18] - Introduction: Dr. Allison Betof Warner at Stanford
[01:34] - Question: How did Lucal help patients with PD-1 resistant melanoma?
[02:35] - Question: In the Tilvince 301 trial, how might measuring overall response and progression-free survival show if lifileucel works better?
[02:49] - Explanation: TILVANCE-301 trial details and frontline potential
[04:23] - Question: What is OBX 115, and how could it make TIL therapy safer?
[04:36] - Explanation: OBX-115 with regulatable mbIL-15 and 67% response rate
[05:56] - Question: How might improving TIL therapy change treatment options for patients?
[06:04] - Explanation: Expanding TIL to other cancers and one-time treatment benefits

Video interviews to be posted from this event at these websites...
https://oncologytube.com/tag/moasc/
https://moasc.org/
https://anco.org/

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