In this high-yield medical education video, we break down milrinone, a phosphodiesterase-3 inhibitor used for inotropic support in heart failure and cardiogenic shock. Whether you're in the ICU, ED, or cardiology service, this is your focused review of how milrinone works and when to use it.
???? In this video, you’ll learn:
What is milrinone and how does it work?
Mechanism of action: PDE-3 inhibition → ↑ cAMP → ↑ inotropy and vasodilation
Receptors and intracellular signaling explained simply
Clinical indications: acute decompensated heart failure, cardiogenic shock, post-cardiac surgery
Differences vs. dobutamine
Side effects: arrhythmias, hypotension, renal clearance issues
When milrinone is preferred in low-output states
Evidence summary + board-style practice questions
???? Perfect for learners preparing for USMLE, Step 2/3, critical care boards, internal medicine, or pharmacy rounds.
???? Related Resources:
Download our milrinone study guide and practice questions: https://www.patreon.com/collection/1443765
Watch next: Playlist Vasopressors and Inotropes:
https://youtube.com/playlist?list=PLf5bMa9_tvRg_nAnm91hsyHhI0y_ahoS1&si=Myz25vHJgHAp4Nvc
???? Like, comment, and subscribe for weekly videos on critical care, emergency medicine, and more!
????????SIGN UP FOR OUR FREE WEEKLY NEWSLETTER????????
https://whiteboardmedicine.kit.com/634ccbe783
????Become a WhiteBoard Medicine member for early access and perks!
https://www.youtube.com/channel/UCiMhM7xCTT8b5SJRnhpH7Ag/join
????DON'T MISS OUT - JOIN OUR PATREON COMMUNITY TODAY ????
https://www.patreon.com/WhiteBoardMedicine
We appreciate the support!
????New WhiteBoard Medicine Podcast!
PodBean - https://whiteboardmedicine.podbean.com
Apple - https://podcasts.apple.com/us/podcast/whiteboard-medicine/id1808306430
Spotify - https://open.spotify.com/show/2PgtF4QpnePOKYUd6RBrqE?si=RnwORi6rQqGRfBpmQ3fg_g
Listen Notes - https://www.listennotes.com/podcasts/whiteboard-medicine-whiteboard-medicine-osU-105r_Y6/?srsltid=AfmBOopY7QsUZLfvSoBV_Aooph-MPgfbXck0T4Fs1Ei5AOUILVkZ3R8J
iHeart - https://www.iheart.com/podcast/1323-whiteboard-medicine-272468908/
COLLECTION OF PLAYLISTS:
Critical Care Medicine ????
https://youtube.com/playlist?list=PLf5bMa9_tvRiZ85NNUGwk91YpqDWdIGvA&si=jGyrxrOcvQqTldFb
Pulmonology????
https://youtube.com/playlist?list=PLf5bMa9_tvRinTHdWwKFYBX7N5kfOBRHz&si=BKliNG26xrQqUNvx
Cardiology and ECG????
https://youtube.com/playlist?list=PLf5bMa9_tvRh2JoODgpLapjGDYXSW1q0h&si=jnr41duxoNnMw4ss
Nephrology????
https://youtube.com/playlist?list=PLf5bMa9_tvRgwXdcj18ux70r08Et93idU&si=tbOHFsPfZgFFZxWg
Acid Base????
https://youtube.com/playlist?list=PLf5bMa9_tvRjj4NDR0eq6M6TqKiZQZChX&si=iC0eBYNRCawR7f0G
Medical, Healthcare, and Science News????
https://youtube.com/playlist?list=PLf5bMa9_tvRhsj4rBQzF7YOtboBoHL2u9&si=OBt6z2aJabzPoLeR
Biostatistics and Research????
https://youtube.com/playlist?list=PLf5bMa9_tvRikRVVVVL09H-GxxrlJiZJh&si=vUO_j8D3VPqGAIAl
Immunology????
https://youtube.com/playlist?list=PLf5bMa9_tvRjLvJPC2ub_mLSxFmL7dNnt&si=RmbzEewJV1YU3PEx
Laboratory Evaluation and Values????
https://youtube.com/playlist?list=PLf5bMa9_tvRjGho7xcGieA1Hdkaj4vCCF&si=6cEOyuA8wuKcdpbp
Infectious Disease????
https://youtube.com/playlist?list=PLf5bMa9_tvRj4G9ApK7nw-7V2Ye31_MR9&si=C-_5_1x7RXrzaTMs
Obstetrics and Gynecology????
https://youtube.com/playlist?list=PLf5bMa9_tvRgYRUdsBVEZ345SY0yYVEl9&si=A0SYAeK637NiMIdu
Procedures????
https://youtube.com/playlist?list=PLf5bMa9_tvRiUYMZbBl-KBJJe2vyoeWyL&si=WJzDSnFd049JgHDc
Endocrinology????
https://youtube.com/playlist?list=PLf5bMa9_tvRgxyOVpxlkKAxsx4mtr6nGx&si=eiLnS5kDySGdHxMP
________________________________________________________________________
If you enjoy the content and feel inclined, here are some ways in which you can support us! Funds will go towards purchasing better equipment/software, dedicating more time to the channel, and continuing to strive towards taking this channel to the next level!
DISCLAIMER THIS VIDEO DOES NOT PROVIDE MEDICAL ADVICE. The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read, watched, or listened to on this video, or any other videos, reports, texts tweets or other sources.
#Milrinone #Inotrope #PDE3Inhibitor #CardiogenicShock #HeartFailure #CriticalCare #ICUPharmacology #MedicalEducation #ShockManagement #InotropeMechanism #LowOutputState #USMLE #InternalMedicine
???? In this video, you’ll learn:
What is milrinone and how does it work?
Mechanism of action: PDE-3 inhibition → ↑ cAMP → ↑ inotropy and vasodilation
Receptors and intracellular signaling explained simply
Clinical indications: acute decompensated heart failure, cardiogenic shock, post-cardiac surgery
Differences vs. dobutamine
Side effects: arrhythmias, hypotension, renal clearance issues
When milrinone is preferred in low-output states
Evidence summary + board-style practice questions
???? Perfect for learners preparing for USMLE, Step 2/3, critical care boards, internal medicine, or pharmacy rounds.
???? Related Resources:
Download our milrinone study guide and practice questions: https://www.patreon.com/collection/1443765
Watch next: Playlist Vasopressors and Inotropes:
https://youtube.com/playlist?list=PLf5bMa9_tvRg_nAnm91hsyHhI0y_ahoS1&si=Myz25vHJgHAp4Nvc
???? Like, comment, and subscribe for weekly videos on critical care, emergency medicine, and more!
????????SIGN UP FOR OUR FREE WEEKLY NEWSLETTER????????
https://whiteboardmedicine.kit.com/634ccbe783
????Become a WhiteBoard Medicine member for early access and perks!
https://www.youtube.com/channel/UCiMhM7xCTT8b5SJRnhpH7Ag/join
????DON'T MISS OUT - JOIN OUR PATREON COMMUNITY TODAY ????
https://www.patreon.com/WhiteBoardMedicine
We appreciate the support!
????New WhiteBoard Medicine Podcast!
PodBean - https://whiteboardmedicine.podbean.com
Apple - https://podcasts.apple.com/us/podcast/whiteboard-medicine/id1808306430
Spotify - https://open.spotify.com/show/2PgtF4QpnePOKYUd6RBrqE?si=RnwORi6rQqGRfBpmQ3fg_g
Listen Notes - https://www.listennotes.com/podcasts/whiteboard-medicine-whiteboard-medicine-osU-105r_Y6/?srsltid=AfmBOopY7QsUZLfvSoBV_Aooph-MPgfbXck0T4Fs1Ei5AOUILVkZ3R8J
iHeart - https://www.iheart.com/podcast/1323-whiteboard-medicine-272468908/
COLLECTION OF PLAYLISTS:
Critical Care Medicine ????
https://youtube.com/playlist?list=PLf5bMa9_tvRiZ85NNUGwk91YpqDWdIGvA&si=jGyrxrOcvQqTldFb
Pulmonology????
https://youtube.com/playlist?list=PLf5bMa9_tvRinTHdWwKFYBX7N5kfOBRHz&si=BKliNG26xrQqUNvx
Cardiology and ECG????
https://youtube.com/playlist?list=PLf5bMa9_tvRh2JoODgpLapjGDYXSW1q0h&si=jnr41duxoNnMw4ss
Nephrology????
https://youtube.com/playlist?list=PLf5bMa9_tvRgwXdcj18ux70r08Et93idU&si=tbOHFsPfZgFFZxWg
Acid Base????
https://youtube.com/playlist?list=PLf5bMa9_tvRjj4NDR0eq6M6TqKiZQZChX&si=iC0eBYNRCawR7f0G
Medical, Healthcare, and Science News????
https://youtube.com/playlist?list=PLf5bMa9_tvRhsj4rBQzF7YOtboBoHL2u9&si=OBt6z2aJabzPoLeR
Biostatistics and Research????
https://youtube.com/playlist?list=PLf5bMa9_tvRikRVVVVL09H-GxxrlJiZJh&si=vUO_j8D3VPqGAIAl
Immunology????
https://youtube.com/playlist?list=PLf5bMa9_tvRjLvJPC2ub_mLSxFmL7dNnt&si=RmbzEewJV1YU3PEx
Laboratory Evaluation and Values????
https://youtube.com/playlist?list=PLf5bMa9_tvRjGho7xcGieA1Hdkaj4vCCF&si=6cEOyuA8wuKcdpbp
Infectious Disease????
https://youtube.com/playlist?list=PLf5bMa9_tvRj4G9ApK7nw-7V2Ye31_MR9&si=C-_5_1x7RXrzaTMs
Obstetrics and Gynecology????
https://youtube.com/playlist?list=PLf5bMa9_tvRgYRUdsBVEZ345SY0yYVEl9&si=A0SYAeK637NiMIdu
Procedures????
https://youtube.com/playlist?list=PLf5bMa9_tvRiUYMZbBl-KBJJe2vyoeWyL&si=WJzDSnFd049JgHDc
Endocrinology????
https://youtube.com/playlist?list=PLf5bMa9_tvRgxyOVpxlkKAxsx4mtr6nGx&si=eiLnS5kDySGdHxMP
________________________________________________________________________
If you enjoy the content and feel inclined, here are some ways in which you can support us! Funds will go towards purchasing better equipment/software, dedicating more time to the channel, and continuing to strive towards taking this channel to the next level!
DISCLAIMER THIS VIDEO DOES NOT PROVIDE MEDICAL ADVICE. The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read, watched, or listened to on this video, or any other videos, reports, texts tweets or other sources.
#Milrinone #Inotrope #PDE3Inhibitor #CardiogenicShock #HeartFailure #CriticalCare #ICUPharmacology #MedicalEducation #ShockManagement #InotropeMechanism #LowOutputState #USMLE #InternalMedicine
- Categoria
- Cardiology
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