(Audio) UroPatient Episode 9: Medical Therapy for Benign Prostatic Hyperplasia (BPH)

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Medical therapy for benign prostatic hyperplasia (BPH) aims to alleviate symptoms, improve urinary flow, reduce the risk of complications, and enhance quality of life. Here are some common medications used in the medical management of BPH:
Alpha-Blockers: Alpha-blockers work by relaxing the smooth muscles in the prostate gland and bladder neck, thereby improving urinary flow and reducing symptoms such as urinary urgency, frequency, and hesitancy. Examples include:
Tamsulosin (Flomax)
Alfuzosin (Uroxatral)
Terazosin (Hytrin)
Doxazosin (Cardura)
5-Alpha Reductase Inhibitors (5-ARIs): 5-ARIs reduce the size of the prostate gland by blocking the conversion of testosterone to dihydrotestosterone (DHT), which is involved in prostate growth. These medications may take several months to achieve noticeable effects. Examples include:
Finasteride (Proscar)
Dutasteride (Avodart)
Combination Therapy: Combining an alpha-blocker with a 5-ARI has been shown to be more effective than either medication alone in improving symptoms and reducing the risk of disease progression. Examples of combination therapy include:
Tamsulosin + Dutasteride (Jalyn)
Alfuzosin + Dutasteride
Phosphodiesterase-5 Inhibitors (PDE5 Inhibitors): PDE5 inhibitors, commonly used to treat erectile dysfunction, have also shown efficacy in improving urinary symptoms associated with BPH. Tadalafil (Cialis) is the most commonly used PDE5 inhibitor for BPH.
*The information provided on the site is for educational purposes only, and does not substitute for professional medical advice. Consult a medical professional or healthcare provider if you are seeking medical advice, diagnoses, or treatment.
Category
Urology
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