Borderline Levels Misleading: Multiple Modest Health Risks More Dangerous | WCCMM TV 2024

"The root cause of cardiovascular disease is not just a single risk factor, but the combination of multiple factors, often at borderline levels," said Dr. Jagat Narula in a conversation with Dr. PC Manoria at the Third World Congress on Cardiometabolic Medicine (WCCMM) 2024.

Here are the key takeaways from their conversation:

1. India Faces High Cardiovascular Morbidity and Mortality Rates
2. Borderline Risk Factors Pose Greater Danger Than Extreme Elevations of a Single Factor.
3. Genetics and Lifestyle Determine ASCVD Prevalence.
4. Ideal LDL Levels Should Be Closer to What We Are Born With.
5. Inclisiran and mRNA Therapeutics Offer New Hope for Lipid Management.

Dr. P.C. Manoria

Dr. P.C. Manoria is a renowned cardiologist and a visionary leader in cardiovascular medicine. As the Director of Manoria Heart & Critical Care Hospital in Bhopal, he has dedicated his career to advancing patient care through innovative treatment strategies and comprehensive cardiovascular programs.

With decades of clinical experience, Dr. Manoria has become a trusted authority in the management of atherosclerotic cardiovascular disease (ASCVD) and metabolic syndromes. His clinical practice is marked by a commitment to preventive cardiology—emphasizing early detection, lifestyle modification, and tailored treatment plans to mitigate cardiovascular risks.

Beyond his clinical work, Dr. Manoria is an active contributor to academic research and frequently shares his insights at international conferences, where he advocates for innovative and sustainable approaches to cardiac care. His leadership in the field has not only influenced patient outcomes in India but has also set benchmarks for cardiology practices worldwide.

Dr. Jagat Narula

Dr. Jagat Narula is a globally acclaimed cardiologist, researcher, and academic leader with a profound impact on modern cardiovascular medicine. Holding an MD, PhD, and MACC, he is currently serving as the Executive Vice President and Chief Academic Officer at UTHealth Houston. In addition to his leadership role at one of the world’s premier medical institutions, Dr. Narula is also serving as the President-Elect of the World Heart Federation, where he plays a critical role in shaping global cardiovascular health policies.

His pioneering work in advanced imaging techniques and risk assessment has transformed the way clinicians diagnose and manage heart disease, particularly in the context of atherosclerosis. He is well known for advocating that aggressive management of LDL cholesterol can significantly reduce cardiovascular events, and his personal approach to maintaining exceptionally low LDL levels has inspired many in the medical community. With numerous publications and a robust presence at international conferences, Dr. Narula continues to drive innovation in cardiovascular research and patient care, cementing his reputation as a thought leader who bridges the gap between groundbreaking science and everyday clinical practice.

LinkedIn: https://www.linkedin.com/in/jagat-narula-md-phd-690865133?lipi=urn%3Ali%3Apage%3Ad_flagship3_profile_view_base_contact_details%3B69a9EhDOS1CZxyT2i0xNCw%3D%3D

00:00 - Starting Montage
00:28 - Introduction
00:50 - ASCVD: An Epidemic in India
01:52 - The Real Culprit: Risk Factors
03:10 - Can Lifestyle Overcome Genetics?
05:02 - What’s the Ideal LDL Level?
07:08 - How Low Is Dr. Narula’s LDL?
07:37 Problem With Medication Compliance
09:11 - The Future: Inclisiran & mRNA Therapies
10:17 - What Is the Polygenic Risk Score?
11:34 - Conclusion & Key Takeaways
11:40 - Ending Montage

#WCCMM2024 #DrPCManoria #DrJagatNarula #ManoriaHeartandCriticalCareHospital #WorldHeartFederation #UTHealthHouston #LDLLevel #ASCVD #BorderlineLevels #Atherosclerosis #PolygenicRiskScores #CardiometabolicHealth #TheRightDoctors #TRD

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