Effect of Fetal Microbiota Transplantation on Immune Tonus

11 Visioni

Grazie! Condividilo con i tuoi amici!

Non hai gradito questo video. Grazie per il feedback!

Published Oct 15, 2025

Join Dr. Marine Fidelle (Laurent Sid Vogel Lab, Gustave Roussy, France) as she discusses groundbreaking research on the role of the gut microbiota in cancer treatment at Olink Proteomics 2024

Key topics covered in this talk:

-How the gut microbiota plays a fundamental role in human health and cancer immunotherapy.
-Evidence showing that antibiotics can reduce the effectiveness of immunotherapy, especially immune checkpoint blockade.
-Discoveries linking gut microbiota composition with patient responses to treatments for lung cancer, renal cancer, and melanoma.
-Identification of beneficial vs. unfavorable bacterial clusters and the development of the **Toposcore** as a predictive tool.
-Insights from fecal microbiota transplantation (FMT) models, showing how microbiota from responders can restore treatment effectiveness in resistant patients.
-The potential of microbiota-centered interventions to improve cancer immunotherapy outcomes.
-Future directions: understanding immune mechanisms, cytokine balance, and how FMT may overcome resistance to therapy.

This research opens the door to new therapeutic strategies that combine microbiota science with oncology, offering hope for patients who currently face limited options.

Register Here for this years event: https://www.labroots.com/virtual-event/opw2025?campaign=OLYT2024