Part 1: LDL Targets in Diabetes – Indian vs Global Guidelines | Dr. Ajit Menon | ACCC’25 Day 1

In this session, Dr. Ajit Menon, Director of Cardiac Sciences at Sir HN Reliance Foundation Hospital, compared global lipid management strategies with the Lipid Association of India (LAI) guidelines, focusing on LDL targets in diabetic patients. He explained how Indian guidelines classify patients into high, very high, and extreme risk categories, with LDL-C goals ranging from less than 70 mg/dL to less than 30 mg/dL, based on ASCVD presence and target organ damage. The session also covered risk-based targets for non-HDL cholesterol and ApoB. Dr. Menon highlighted newer non-statin therapies such as bempedoic acid, PCSK9 inhibitors (evolocumab and alirocumab), and inclisiran—a novel siRNA therapy that offers sustained LDL reduction. Supported by landmark trials like FOURIER, ODYSSEY, and ORION, the talk emphasized the importance of aggressive LDL lowering in diabetes to reduce cardiovascular risk.

???? Part 2 is now live – watch it for real-world treatment responses, case insights, and long-term outcomes.

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