Proton vs Photon Radiotherapy for Oropharyngeal Cancer | HN Oncology Journal Club Ep 008

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First phase 3 RCT comparing proton therapy to photon therapy for head and neck cancer (Frank et al., Lancet 2025).

https://hnoncology-journalclub.netlify.app/

Key findings:
- Non-inferiority achieved for progression-free survival
- 42% reduction in death risk with protons (HR 0.58, p=0.045)
- 33% reduction in feeding tube dependence

Full episode & newsletter: https://hnoncology-journalclub.netlify.app/episode-008.html
Paper: https://doi.org/10.1016/S0140-6736(25)01962-2

#HeadAndNeckCancer #ProtonTherapy #RadiationOncology #Oncology #MedicalEducation
Categoria
Oncology
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