What’s New in Pancreatic Cancer? Early Data from the TWINPEAK Bispecific Antibody Study

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Join GI oncology experts Dr. Anwaar Saeed (University of Pittsburgh), Dr. Zev Wainberg (UCLA), and Dr. Teresa Macarulla (Vall d’Hebron Institute of Oncology, Spain) as they discuss early findings from the TWINPEAK trial, presented at ASCO GI 2026 in San Francisco.

✅ Early efficacy and safety data of Spevatamig, a first-in-class bispecific T-cell engager targeting Claudin 18.2 and CD47 in gastrointestinal cancers, including pancreatic cancer
✅ Tested as monotherapy or in combination with chemotherapy (gemcitabine) or immunotherapy
✅ Promising clinical results
✅ Bispecific antibody advantages: Engaging innate immunity and overcoming treatment resistance in pancreatic cancer
✅ Future directions: Potential combinations with KRAS inhibitors, PD-1 inhibitors, and other immunomodulators
✅ Global perspectives on where this therapy fits in current and future GI cancer treatment paradigms

The interview is sponsored by Phanes Therapeutics

#cancerresearch #CancerScience #Oncology #MedicalResearch #PancreaticCancer #GIOncology #BispecificAntibodies #ImmunoOncology #ClinicalTrials #CancerInnovation #TwinPeakTrial #TargetedTherapy #OncologyExperts #FrontlineTherapy #ChemoImmunotherapy #Claudin182 #NovelTherapies #OncologyExperts #ASCO

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