????Exploring ADCs in Platinum-Resistant Ovarian Cancer: Prof Ray-Coquard & Dr Agustí & Dr Strojna

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????Exploring ADCs in Platinum-Resistant Ovarian Cancer: Advancements and Patient
????Interviewee: Prof. Isabelle Ray-Coquard
????Interviewer: Dr. Núria Agustí & Dr. Aleksandra Strojna

0:58 ❓In the context of platinum resistance in ovarian cancer, what are the key advantages of using antibody–drug conjugates (ADCs) over traditional chemotherapy regimens?

2:03 ❓Given the data from trials like FORWARD I, SORAYA, and especially MIRASOL, what have we learned about the optimal patient population for ADC therapy in ovarian cancer?

2:47 ❓Regarding the tumor heterogeneity, would you consider re-biopsy of the tumor in cases of low antigen expression? How does that heterogeneity and potential antigen loss affect ADC efficacy?

3:29 ❓Could you share the main efficacy results comparing mirvetuximab soravtansine to standard chemotherapy, in terms of PFS and OS?

4:28 ❓Looking ahead, what future trials or research directions do you believe will be most critical in advancing the use of ADCs in ovarian cancer?

✨The International Journal of Gynecological Cancer (IJGC) is the primary educational and informational publication for topics relevant to detection, prevention, diagnosis, and treatment of gynecologic malignancies. Its content is read by gynecologists, medical oncologists, radiation oncologists, radiologists, pathologists, and research scientists with a special interest in gynecological oncology. IJGC emphasizes a multidisciplinary approach and includes original research, reviews, and video articles.

ℹ️IJGC is the official journal of the International Gynecologic Cancer Society and the European Society of Gynaecological Oncology

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Category
Oncology
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