Expert Cancer Panel: Transplant-eligible male with extensive relapsed classical Hodgkin lymphoma

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Published
Recorded on 7/24/2021

61 year old transplant-eligible male with extensive relapsed classical Hodgkin lymphoma

Summary:
- The goal for transplant-eligible patients with relapsed, chemotherapy-sensitive classical Hodgkin lymphoma is salvage chemotherapy followed by autologous stem cell transplantation.
- Ifosfamide, carboplatin, and etoposide (ICE) is a commonly used salvage chemotherapy regimen, with plans for PET-CT restaging after two cycles prior to stem cell collection.
- For patients that are transplant ineligible (e.g., less fit and/or elderly), options include anti-PD-1 antibodies (pembrolizumab and nivolumab) as monotherapy, the anti-CD30 antibody drug conjugate brentuximab vedotin as monotherapy, or a combination of agents from these two classes.


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Oncology
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