Expert Cancer Panel: Stage IIA thymoma s/p surgery w/ close margins & microscopic capsular invasion

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Published
Recorded on 9/9/2022

49-year-old woman, never smoker, with history of papillary thyroid cancer status post resection and radioactive iodine in 2011, now with recently resected Masaoka Stage IIA WHO Type B2 thymoma with close margins (0.1 mm deep margin). Tumor measured 4.5 x 3.5 x 1.7 cm in anterior, superior mediastinum with microscopic capsular invasion

Summary:
- Re-resection, as well as adjuvant radiation, are not advised without clear understanding of the precise location of the close margin.
- Adjuvant systemic chemotherapy is not recommended.
- Imaging surveillance should be done every 6 months for 1-2 years, and then annually, potentially continuing beyond 5 years as thymoma can recur many years after diagnosis. MRI chest could be used, alternating with CT, particularly in young patients to minimize radiation exposure.


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Category
Oncology
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